This study investigated perceived influence of social media use on child-rights advocacy in Ondo State. The study was guided by five objectives. Anchored on Agenda-setting Media theory and Social Marketing theory, the study was conducted with survey method with a population of 1,440 and a sample of 360. Findings of the study revealed that respondents are well aware of the child-rights advocacy in the various social media such as Facebook, Twitter, Instagram, WhatsApp which are more frequently, used than traditional channels of communication such as radio, television, newspaper etc. The social media give opportunities to its users to participate in discussion. The challenges of social media on child-rights advocacy are cost of smartphones, data purchase, maintenance, frequent power outage, internet service failure and the fact that some website owners or bloggers do not show interest in child-rights advocacy. Respondents opined that child-rights advocates should not limit their advocacy to only social media. They want import duties on smartphones and their accessories reduced and that federal government should address the problems of power failure so that the social media users can re-power their devices. The study therefore recommended that children at all levels should be more enlightened on the issues of child-rights to awaken them to their rights. Parents or guardians should be more enlightened on child-rights laws through other channels of communication.